To answer your questions :
Driveability : More power and it's noticeable. Car doesn't struggle as it used to.
Economy : About the same, maybe a bit worse, but that's more because I can't tell right now due to a buggered fuel gauge. Going a different gear than 3.55 or larger tire would amend this. My old car used to get solid mileage with a properly tuned 4.2 and MC2100, I think it was close to 23MPG. I'd go out on a limb to say I'd getting less than that now by a few MPG.
Durability : The engines are about the same, but the newer 4.0 gets more oil to the 6th cylinder, has a better flowing head as well. Both excellent engines. I'd have 0 worries about either motor to be honest, they are known to take a severe beating and last well into the 3-400 000 mile range.
Having run both though, the 4.0 wins over the 4.2. I did carb mine for shits and giggles but it wasn't tuned properly. Ran fine though, so if you decide to just swap the motor and keep the stock drivetrain it's an option and DOES increase the power. A solid option for you would be a head swap.
You also have to look at your transmission, transfer case, axle gearing as well. Are you sticking with the stock 998, going 727, AX15 or AW4? NP231, NP242, or the stock NP12x?
If I had the cash, I'd have my 4.0L stroked, run a AX15 (or maybe still the AW4) with the NP242 and keep it fuel injected and run the 3.55 gears I have now.
As it is now, the 4.0 / AW4 / NP242 / 3.55 combo is pretty good. More than enough to keep that old bird flying and definitely a difference that can be noticed. It can actually crawl through this deep crap snow without a problem, the old drivetrain I had to slam the pedal down.
I'm still debating swapping the gears out for a shorter gear, something in the lower 3.xx range. This car isn't too much for offroading and sees more on road travel.
In the end, a properly tuned 4.2L with a solid ignition system and a good carb will provide more than enough performance and reliability. The only reason I changed all mine out is because I'm retarded. They drive very similarily. The stock 4x4 on the Eagle is sickeningly capable as well, moreso than a lot of people realize. It *is* a true 4x4, albeit no low range, and I've had it rolling through 3 feet of water, with 1/3 of that mud at the bottom, 3-4 feet of snow, along roads with torrential downpours, and so forth. And it ran like a boss.
Only thing I hated was the carb in the cold, and I live in Canada...that ended up being a huge selling point for me.